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​In patients taking cyclosporine or the HIV protease inhibitor tipranavir plus ritonavir or the hepatitis C virus (HCV) protease inhibitor glecaprevir plus pibrentasvir or letermovir when co-administered with cyclosporine, therapy with LIPITOR should be avoided. Medically reviewed by Drugs.com. Take the medicine at the same time each day. Grapefruit and grapefruit juice may interact with atorvastatin and lead to potentially dangerous effects. Does Lipitor work better if you take it at night? -Atorvastatin dose should not exceed 20 mg/day when coadministered with clarithromycin, itraconazole, saquinavir plus ritonavir (use lowest dose necessary), darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir, elbasvir plus grazoprevir, letermovir Zetia, simvastatin, fenofibrate, Lopid, rosuvastatin, Lipitor, Crestor, ezetimibe, pravastatin, evolocumab. Minimize drinking alcohol. Follow your doctor's instructions very closely. LIPITOR should be used as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) in these patients or if such treatments are unavailable. Patients who require a large reduction in LDL-C (more than 45%) may be started at 40 mg once daily. LIPITOR can be administered as a single dose at any time of the day, with or without food. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Serious drug interactions can occur when certain medicines are used together with atorvastatin. Atorvastatin drug interactions (in more detail). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use atorvastatin only for the indication prescribed. Atorvastatin dosage information (in more detail). Call your doctor for medical advice about side effects. Maximum dosage: 20 mg once per day. Atorvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using. Available for Android and iOS devices. Copyright 1996-2020 Cerner Multum, Inc. LIMIT atorvastatin dose to 20 mg/day with concomitant use of clarithromycin, itraconazole, elbasvir plus grazoprevir, or with HIV combinations of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, or fosamprenavir plus ritonavir; appropriate clinical assessment is recommended to ensure the lowest effective dose is employed Atorvastatin side effects (in more detail). kidney problems - little or no urinating, swelling in your feet or ankles, feeling tired or short of breath. In patients with HIV taking lopinavir plus ritonavir, use the lowest dose necessary of LIPITOR. Do not take extra medicine to make up the missed dose. Adjustments should be made at intervals of 4 weeks or more. In patients taking clarithromycin, itraconazole, elbasvir plus grazoprevir, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir or letermovir therapy with LIPITOR should be limited to 20 mg, and appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used. Child dosage (ages 0–9 years) Atorvastatin hasn’t been studied in children younger than 10 years of age for this purpose. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The combination of HMG-CoA reductase inhibitors (statins) and fibrates should generally be used with caution [see Warnings and Precautions (5.1) and Drug Interactions (7)]. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. LIPITOR may be used with bile acid resins. You may not notice any change in your symptoms, but keep using the medication as directed. Medically reviewed by Sanjai Sinha, MD. Do not use this medicine in larger or smaller amounts or for longer than recommended. Atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. Computer 'Nudge' Spurs Doctors to Prescribe Statins to Heart Patients, Statins Going Generic Saved Medicare Billions. Your doctor may occasionally change your dose to make sure you get the best results. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Follow your diet, medication, and exercise routines very closely. In patients with HIV taking lopinavir plus ritonavir, use the lowest dose necessary of LIPITOR. Stop taking this medication and tell your doctor right away if you become pregnant. The recommended starting dose of LIPITOR is 10 or 20 mg once daily. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Atorvastatin side effects Get emergency medical help if you have signs of an allergic reaction to atorvastatin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. For oral dosage form (tablets): For high cholesterol: Adults—At first, 10 or 20 milligrams (mg) once a day. In patients taking the HIV protease inhibitor nelfinavir therapy with LIPITOR should be limited to 40 mg. Is Repatha (evolocumab) effective without a statin. trouble lifting your arms, trouble climbing or standing; liver problems - upper stomach pain, weakness, tired feeling, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes); or. Doses should be individualized according to the recommended goal of therapy [see Indications and Usage (1.2) and Clinical Pharmacology (12)]. Atorvastatin is only part of a complete treatment program that may also include diet, exercise, and weight control. Atorvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins.". Children 10 to 17 years of age—At first, 10 mg once a day. Atorvastatin is used in adults and children who are at least 10 years old. Patients who require a large reduction in LDL-C (more than 45%) may be started at 40 mg once daily. The dosage range of LIPITOR is 10 to 80 mg once daily. Generic name: ATORVASTATIN CALCIUM TRIHYDRATE 10mgDosage form: tablet, film coated. Are Statin Side Effects 'All in Your Head'? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. The starting dose and maintenance doses of LIPITOR should be individualized according to patient characteristics such as goal of therapy and response. Do not use if you are pregnant. We comply with the HONcode standard for trustworthy health information -. Some patients may need to start at 40 mg per day. To make sure this medicine is safe for you, tell your doctor if you have ever had: if you drink more than 2 alcoholic beverages daily. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. Computer 'Nudge' Spurs Doctors to Prescribe Statins to Heart Patients, Statins Going Generic Saved Medicare Billions. Crestor, Zetia, atorvastatin, simvastatin, fenofibrate, Lopid, rosuvastatin, ezetimibe, pravastatin, evolocumab. You may report side effects to FDA at 1-800-FDA-1088. Atorvastatin is not approved for use by anyone younger than 10 years old. Store at room temperature away from moisture, heat, and light. Last updated on Nov 5, 2020. Is Repatha (evolocumab) effective without a statin. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. When co-prescribing atorvastatin with other protease inhibitors, appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used, We comply with the HONcode standard for trustworthy health information -. Renal disease does not affect the plasma concentrations nor LDL-C reduction of LIPITOR; thus, dosage adjustment in patients with renal dysfunction is not necessary [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.3)]. The dosage range of LIPITOR is 10 to 80 mg once daily. After initiation and/or upon titration of LIPITOR, lipid levels should be analyzed within 2 to 4 weeks and dosage adjusted accordingly. LIPITOR can be administered as a single dose at any time of the day, with or without food. Not all possible interactions are listed in this medication guide. Are Statin Side Effects 'All in Your Head'? Last updated on Oct 7, 2020. Get emergency medical help if you have signs of an allergic reaction to atorvastatin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In patients taking cyclosporine or the HIV protease inhibitor tipranavir plus ritonavir or the hepatitis C virus (HCV) protease inhibitor glecaprevir plus pibrentasvir or letermovir when co-administered with cyclosporine, therapy with LIPITOR should be avoided. Also call your doctor at once if you have: muscle weakness in your hips, shoulders, neck, and back. Generic Name: atorvastatin (a TOR va sta tin) Atorvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. You should not take atorvastatin if you are pregnant or breastfeeding, or if you have liver disease. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid). How long does atorvastatin stay in the system after stopping the drug? In patients taking the HIV protease inhibitor nelfinavir therapy with LIPITOR should be limited to 40 mg. You may need to take atorvastatin for a long time or for life depending on your medical history. Available for Android and iOS devices. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. Select one or more newsletters to continue. Atorvastatin is usually taken once a day, with or without food. Stop taking this medicine and tell your doctor right away if you become pregnant. Atorvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Avoid eating foods that are high in fat or cholesterol. Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them. Take atorvastatin exactly as prescribed by your doctor. How long does atorvastatin stay in the system after stopping the drug? In patients taking clarithromycin, itraconazole, elbasvir plus grazoprevir, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir or letermovir therapy with LIPITOR should be limited to 20 mg, and appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The recommended starting dose of LIPITOR is 10 mg/day; the usual dose range is 10 to 20 mg orally once daily [see Clinical Studies (14.6)]. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Your blood work will help your doctor determine how long to treat you with atorvastatin. The dosage of LIPITOR in patients with HoFH is 10 to 80 mg daily. Also call your doctor about all your current medicines and natural products not take extra medicine to make you!, alerts and updates ages 0–9 years ) atorvastatin hasn ’ t studied! Leading to kidney failure long to treat you with atorvastatin, simvastatin, fenofibrate Lopid. Poison help line at 1-800-222-1222 the Poison help line at 1-800-222-1222 personal circumstances than prescription. 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